Retinoic acid on stage in antitumor immunity
نویسندگان
چکیده
The morphogenic role of retinoic acid (RA) in regulating immunity is underscored by our recent studies that show increased regional concentrations of RA and commensurate RA signaling in CD8+ T cells within the tumor microenvironment. This study demonstrated for the first time that intrinsic RA signaling is required for tumor associated antigen (TAA)-specific CD8+ T-cell survival and hence for tumor surveillance.
منابع مشابه
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013